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Montelukast can cause different side effects at varying degrees such as gastrointestinal disturbances, hypersensitivity or allergic reactions, sleep disorders, stomach upset, diarrhea, cough, dizziness, headache, nausea, vomiting, heartburn, hives and hoarseness of voice. Montelukast can be given in combination with other asthma medications, and it does not interact with warfarin or theophylline.

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"Prednisone is used as replacement therapy in patients whose adrenal glands are unable to produce sufficient amounts of cortical. Prednisone and Prednisolone are members of the glucocorticoid class of hormones. Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly."

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